Programs not opening

I recently updated to 14.3 .
The only thing that opens is Firefox, when i try to open thunar it says "input/output error"
And when I do nitrogen --restore to get my background it fails too.
 
In order to get help, you need to give us much more information than "it fails too". What exactly fails? What are the symptoms? What system calls is nitrogen doing? What are the error codes on those system calls?

The fact that thunar is reporting "input/output error" makes it seem likely that the basic problem is hardware. Have you checked things like dmesg, syslog, or smart whether the underlying hardware is OK? What operation that thunar tries causes an IO error?
 
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