Well, this probably qualifies as "hand cranked".
An 8-bit ISA bus dual 12-bit burr-brown DAC card for the IBM PC, designed by yours truly around 1986-7. This was a prototype, hand-taped 2-layer pth PCB, hand soldered. No CAD was used, the circuit was designed on paper and then the board layout designed on clear film with transfers, which was passed to the PCB shop to construct the board itself, which was a pretty primitive method even back then; we couldn't afford a CAD at the time (and software used to be so expensive!). The board also had an 8-bit PIO port (the IDC socket), and featured its own local split-rail power supply using a DC-DC converter and low power voltage regulators, the board had to produce both +ve and -ve output voltages wrt ground. The two phono socket outputs were DAC-generated control voltages for another piece of equipment. I can't remember what the 3.5 mm jack socket was for. Those were the days; you would never get away with a pcb layout like that nowadays; well, I guess it's not too bad, too slow to worry about reflections etc. It all worked fine, amazingly enough.
The PC used to be a great platform for prototyping bits of hardware like this. It's nowhere near as easy with the modern pci-e stuff, sadly; nowdays you have to faff around with USB, or make the whole thing on an arduino or pi daughter board and talk to it remotely from the PC. This particular board had some calibration software written for it in assembly (using the trimmer pots you can see along the top edge), and there was other software used to drive it and the voltage-controlled external equipment. The PIO port also connected to the external equipment, which was a microprocessor controlled video pattern generator. The analogue voltage outputs of this card had to be time stable and reliably reproducible to 1 part in 1000, ie +/- 1V accurate to 2 mV. Sadly I no longer have the circuit diagram, lost in the mists of time. It's a real shame modern motherboards don't include an ISA slot so you could still do this kind of thing. I know you can get "industrial" motherboards with ISA slots but they are not mainstream PC motherboards.
Various different models, mostly classic series thinkpads. I can't be bothered to sell them for a few quid on ebay, they're not worth anything anyway, and you never know when they're going to come in useful. No company makes this kind of high quality hardware any more, including the modern lenovo thinkpads, so I'm hanging on to them; at least they don't take up very much space. And they all run freebsd!
