Solved ipv4 Network Issues after Upgrade from 12.1->12.2

After updating to 12.2-RELEASE my box no longer can reach a default route for ipv4. ipv6 seems to autoconfigure, but ifconfig does not show an inet entry. I have been able to fix it manually, but it requires me to do it after every reboot.

Manual Fix after reboot:
sudo setfib 0 route add default
sudo service netif restart
sudo dhclient em0

My /etc/rc.conf:
ifconfig_em0="inet netmask"
ifconfig_em0_ipv6="inet6 accept_rtadv"

# set up bridge interface for iocage

# plumb interface em0 into bridge0
ifconfig_bridge0="addm em0 up"

Can anyone help with this?
Why are you running dhclient(8) when you have set a static IP address? Also note that restarting netif will result in routes getting removed, so you're undoing the previous route(8) command.

Your second ifconfig_em0 in your rc.conf overrules the first. Remember that rc.conf is basically just a shell script and you're only setting variables there. The second assignment of the variable simply overwrites whatever the first did. Remove the ifconfig_em0="up".