Then I'd suggest to first reduce the convoluted configuration to the absolute minimum (the only really necessary setting is probably zfs ashift).
If that does not fix the issue, then open a new thread with a concise title "Upgrade to 12.2: Audio no longer works after suspend/resume", which indicates that you had it working, and that the problem is possibly-probably caused by the upgrade, and include your configuration in spoilers (see the editor menu, click the hamburger, then choose spoiler).
If that does not fix the issue, then open a new thread with a concise title "Upgrade to 12.2: Audio no longer works after suspend/resume", which indicates that you had it working, and that the problem is possibly-probably caused by the upgrade, and include your configuration in spoilers (see the editor menu, click the hamburger, then choose spoiler).