Depends on what are your response and legal requirements. Data centers closer to your users will usually have lower latency, which may or may not be relevant to you. Legal requirements are harder to quantify, but assuming you only cater to US users go with an US data center. If you serve EU users stick with EU data centers and depending on what you are serving EU based providers.When picking a hosting provide, how signficance should be attached to the geolocation of the provider?
Does it make much difference? If the majority of users are US based would it have much of a detrimental impact if the hosting company was in Europe?
Depends on what are your response and legal requirements.
For EU for example, if you store personal identifiable information about your users? You have to comply with the GDPR.How to detemine legal requirements?