Which is the best mail server software?

sendmail suits my needs - it does everything I want and allowed me to add milters for anything it doesn't do (I wrote a C milter for it to block spam based on the relay name/IP).
 
For SMTP i'm using exim (switched from postfix because it was unable to suit my needs of mail processing), and for POP3 / IMAP i'm using Сyrus-Imapd. But it all depends on what mail system you're trying to build. How many users (and then - what type of DB for authentication - SQL/LDAP?)? Preferred SPAM fighting software? Webmail frontend? Specific mail processing (i.e. rewriting addresses, saving all mail, etc)?
 
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