Performance is fine on Dell R430s and R640s that I use for Apache, MySQL and PHP, but YMMV - very much depends on your use case.
I don't know what X2APIC is, but haven't noticed its abscence. It might be there and working for all I know. Is it in regards to any particular PowerEdge generation?
I've got a Dell R450 to set up but only got as far as finding out that the RAID controller is no longer viewable under MEGACLI/STORCLI (there's a new PERCCLI tool that isn't available for FreeBSD) and that the 10G NIC drivers aren't quite right (that was under 13.1 or so; I need to go back and try with 14.0).
Netflix use and push performance on FreeBSD (but I don't think they use Dell PowerEdge).